In no particular order

1. Run a marathon
2. Live a year in Italy
3. Graduate university
4. Train travel through Russia
5. Spend a summer in Greece
6. Jump off an aeroplane
7. Bungee-jump of a bridge
8. Eat a croissant in Paris
9. Learn to play your favourite instrument
10. See an active volcano
11. Learn Italian 
12. Visit a tropical rainforest
13. Walk on the Chinese Wall
14. See the Statue of Liberty
15. Visit the Auschwitz Museum in Poland
16. Go watch the Olympics
17. See the Eiffel Tour at night
18. Create your family tree
19. Publish a book
20. Raise a child
21. Plant a tree
22. Sleep in an overwater bungalow in Bora Bora
23. Make someone happy
24. Donate blood
25. Get a tattoo
26. See the sunset in Santorini, Greece 
27. Spend a summer on an exotic island
28. Learn a new language from zero
29. Work in a museum
30. Raise and train a dog
31. Drink tea at 5 o’clock in London
32. Swim with dolphins
33. Visit the eternal city – Rome
34. Swim under a waterfall
35. Move to a new country 
36. Fly in a hot air balloon
37. Be part of a traditional Indian wedding 
38. Learn to use a gun
39. Swim in all 5 oceans
40. Spend time volunteering in Africa
41. Create a family recipe
42. Go on a road trip from California to New York
43. Let go of a floating lantern
44. See the Monarch Butterfly migration
45. Get a PhD
46. Visit the Taj Mahal, India
47. Get an autograph from your favourite musician
48. See the Pyramids, Egypt
49. Speak to an audience of 500 people
50. Learn to cook from your mom/grandma
51. Visit Barcelona, Spain
52. Experience Christmas in New York City
53. See an opera in Sidney, Australia
54. See the Gran Canyon, USA
55. Fly on first class
56. Visit Istanbul with a history teacher
57. Visit Tokyo, Japan
58. Go paragliding
59. Go to an airport and buy a random flight
60. Keep a diary
61. Have a birthday party in Las Vegas
62. Visit Heaven’s Gate, China
63. Watch a Cirque du Soleil live show
64. Once a year go to a place you’ve never been before
65. See the oversaturated green hills of Yorkshire
66. Visit Louvre, Paris
67. Go on a Mediterranean Cruise
68. Dip your toes in the Indian Ocean
69. Take a ride in the London Eye
70. Be part of a play or movie
71. Visit Malta
72. See a lavender field in Provence, France
73. Get married
74. Try scuba diving in an exotic location
75. Visit the castles in the Loire Valley, France
76. Learn to cook the traditional dish of the country of your birth
77. Solve the Rubik’s Cube
78. Go on a holiday with your mom only / dad only
79. Set foot in the desert
80. Visit Transylvania, Romania
81. See Coldplay in a live concert
82. See the Hollywood mark
83. Watch a Spanish bullfight
84. Spend a full year with your parents
85. Learn World Geography
86. Help at least one orphan
87. Become fluent in French
88. Go on a bike trip across your country
89. Spend the Night in Martha’s Vineyard, Massachusetts
90. Learn to drive
91. Help at least one elderly
92. Learn about World Religions
93. Be the first at something
94. Learn self-defence
95. Spend a year in Japan learning about their culture
96. Create your personal library
97. Start a collection
98. Visit Antarctica
99. See the Northern Lights
100. Visit Tuscany, Italy
101. Visit Cuba and smoke a cigar
102. Visit Svalbard – Arctic Circle
103. Pray in Jerusalem at the Western Wall
104. Go on an African safari
105. Go on a road trip on the Pacific Coast Highway
106. Party in Ibiza, Spain
107. Live a while in New York City, USA
108. Walk on Golden Gate, San Francisco
109. Bath in the Blue Lagoon, Iceland
110. Go to a fashion week (Paris, New York, Rome, Milan)
111. Explore the ruins of Petra, Jordan
112. Go on a Nile cruise to Abu-Simbel
113. Take a trip on the Orient Express
114. Catch a Broadway show in New York
115. Go island hopping in Greece
116. Take part in the annual Oktoberfest, Munich
117. Visit the Galapagos Islands, Ecuador
118. Explore Patagonia’s glaciers from Argentina or Chile
119. Go on a technology-free holiday
120. Touch an iceberg
121. Sleep in a traditional hanok in Jeonju, Korea
122. Discover the tiles of Porto in Portugal
123. Go to a World Cup
124. Visit the Griffiths Observatory, LA
125. Roll the dice in a Las Vegas Casino
126. Travel back in time on Easter Island
127. Hike the Matterhorn Trail, Matterhorn in Zermatt
128. Visit the White House
129. Soak up the spirit of New Orleans at the Mardi Gras Festival
130. Feel the mist of Niagara Falls
131. Go on a romantic gateway to Vermont
132. Float in the Dead Sea
133. Hike through the Himalayas
134. Ride a motorcycle in Bangkok
135. Spend Saint Patrick’s Day in Dublin, Ireland
136. Climb the Kilimanjaro
137. Watch the Serengeti migration from a hot-air balloon
138. Release baby turtles back into the ocean
139. Hug a baby panda in Chengdu, China
140. Visit the Forbidden City, Beijing
141. Meet a geisha
142. Go to a Super Bowl
143. Watch a football game at Wembley, London
144. Visit Madame Tussaud, London
145. Visit Pompei, Italy
146. Experience a traditional Thanksgiving
147. Create your own signature dish
148. Visit the National History Museum, New York
149. Savour dinner at a Michelin Star restaurant
150. Eat at a restaurant on your own
151. Eat Indian food with your hands
152. Walk on the famous Walk of Fame
153. Have fun at Walt Disney World
154. Visit Disneyland Paris
155. Try molecular gastronomy
156. Thank a waiter with a 100% tip
157. Eat roast goat with the Maasai in Kenya
158. Learn to use chopsticks
159. Climb the Haiku Stairs of Oahu, Hawaii
160. See the flamingos on a beach
161. Become someone’s godmother/godfather
162. Order room service
163. Gamble at a Monte Carlo Casino, Monaco
164. Find yourself in a postcard in Portofino, Italy
165. Step foot in the Red Square, Moscow
166. Sleep in a Tuscan villa in Italy
167. Experience the Fall Foliage, New England
168. Walk through the Wisteria Tunnel at Kawachi Fuji Gardens, Japan
169. Stay at the boat hotel in Cocoa Island, Maldives
170. Eat in a three Michelin stars restaurant
171. Pay off someone else’s debt
172. Visit Mount Rushmore, South Dakota
173. Visit the Van Gogh Museum, Netherlands
174. Sit on the edge of Preikestolen, Norway
175. Eat pizza in Chicago
176. Set foot in a place from the Bible (Mount of Olives, Bethlehem, Nazareth)
177. See the Sky Gardens, Singapore
178. Visit Trinity College Library, Dublin
179. Watch a Formula 1 race live
180. See the Seven Sisters Cliff, England
181. Visit a chocolate factory in Switzerland
182. Let go of a floating lantern at Yi Peng Festival, Thailand
183. See Gaudi’s La Sagrada Familia, Barcelona
184. Ride the Trans-Siberian Railway
185. Hear the call to prayer at the Blue Mosque in Turkey
186. Flip a house
187. Visit Lake Como, Italy
188. Shop at a floating market in Vietnam
189. Stand in Time Square, New York
190. Ride on a cable car in San Francisco
191. Start your own scholarship fund
192. Become a self-made millionaire
193. Get a second citizenship
194. Walk on a pink sand beach in the Bahamas
195. Tour Patagonia, Argentina, Chile
196. Give back to charity
197. Visit Stonehenge, England
198. Visit the historic Centre of Old Tallinn, Estonia
199. Experience a carnival in Rio de Janeiro, Brazil
200. Eat paella in Andalusia, Spain
201. Visit Marrakesh, Morocco
202. Go to a Cannes Film Festival in France
203. Visit the archaeological site of Delphi, Greece
204. Experience Macy’s Thanksgiving Day Parade, New York
205. Visit the Picasso Museum in Malaga, Spain
206. See the cherry blossom in Japan
207. Stroll through Sagano Bamboo Forest, Japan
208. Fly in a private jet
209. Visit Mostar, Bosnia & Herzegovina
210. Stay up talking to someone until the sun rises
211. Purchase a piece of artwork
212. Experience Pingxi Lanter Festival, Taiwan
213. Practice calligraphy
214. Visit the Hermitage Museum, St Petersburg, Russia
215. Pose with the Leaning Tower of Pisa, Italy
216. Experience La Tomatina festival, Spain
217. Climb Fiji Mountain, Japan
218. Hike the cities of Cinque Terre, Italy
219. Walk on a glass beach
220. Take a train from the Grand Central Station, New York
221. Relax on a spa gateway
222. Become vegetarian for a month/a year
223. Experience a Tea Ceremony with a grandmaster in Japan
224. Visit Sri Lanka – Golden Valley of the Ceylon Tea
225. Eat a meal cooked by a famous chef
226. Visit a perfume factory in France
227. See penguins in their natural habitat
228. Explore the French Riviera
229. Visit the Maldives
230. Visit the Palace of Versailles, Paris
231. Get stoned in Amsterdam
232. Go wine tasting in Napa Valley, California
233. Drive a luxury car on Italy’s Amalfi Coast
234. Take a train journey through the heart of Africa
235. See the statue of Jesus the Redeemer in Rio de Janeiro, Brazil
236. Go to a classical music concert in Vienna, Austria
237. Take part in a ball in Vienna
238. Go on a holiday with a complete stranger
239. Visit 100 UNESCO World Heritage
240. Hear the Pope pray in Vatican City
241. Stroll through Antigua, Guatemala
242. See a tulip field in the Netherlands
243. Walk through a rice terrace in Indonesia
244. Ski in the Swiss Alps
245. Drink at a Guinness Brewery in Ireland
246. Visit the Large Hadron Collider in Switzerland
247. Do the famous Route 66
248. Explore the Italian Riviera
249. Visit a US National Park
250. Stay at a Beverly Hills hotel in California
251. Take the Walk of Faith, Tianmen Mountain, China
252. Swing at the “End of the World”, Ecuador
253. Make a wish at the Trevi Fountain, Rome
254. Watch the changing of the guard at Buckingham Palace, London
255. Sunbathe topless on the French Riviera
256. Hear Andrea Bocelli sing opera live
257. Walk across Abbey Road in London
258. Attend mass at the Notre Dame Cathedral, Paris
259. Visit a temple
260. Walk on a glacier
261. Taste a Sicilian lemon
262. Host a Christmas dinner for your loved ones
263. Eat seafood
264. Visit all 50 USA 
265. Work in a library
266. Visit Machu Picchu, Peru
267. Throw a dart at a map and go
268. Paint and host your own exhibition
269. Collect sand from all the seas and oceans of the world
270. See a New Year’s Concert in Vienna, Austria
271. Visit Vatican City
272. Set foot on all seven continents
273. Tour a Mayan Ruin
274. Become a CEO
275. Teach someone to read and write
276. Spend Christmas with your family
277. Take part in a Venetian Carnaval, Italy
278. Make an anonymous donation
279. Spend a full day in bed reading a good book
280. Learn yoga and meditation
281. Volunteer
282. Take a solo holiday
283. Take a trip around the World in 80 days
284. Start your own business
285. Spend a summer in the countryside
286. Feed a tiger cub 
287. Win a Nobel Prize 
288. Buy your own house and decorate it
289. Swim in an ocean at night
290. Visit Ireland
291. Fly in a helicopter
292. Make someone laugh until they cry.
293. Celebrate a same-sex marriage.
294. Meet a world leader
295. Spend time with a person from another generation
296. Play matchmaker
297. Practice winter sports
298. Take a Zumba class
299. Go on a submarine
300. Take a train journey coast to coast in Africa
301. Ride a camel
302. Attend a black-tie gala
303. Make a gingerbread house
304. Keep in touch with old friends
305. Read the world’s literature
306. Create a documentary and publish it
307. Laugh until your tummy hurts
308. Visit Hohenzollern Castle, Germany
309. Achieve your ideal weight
310. Fly a kite
311. Go on a yoga retreat
312. Visit Dracula’s Castle in Transylvania, Romania
313. Learn to dance tango
314. Give up a bad habit
315. Go camping and sit around a fire 
316. Learn sign language
317. Get a standing ovation
318. Visit Madeira, Portugal
319. Go on a blind date
320. Toss pizza dough in the air
321. Be on the New York Times Bestseller list
322. Experience Amish Country
323. Reconnect with an old friend
324. Get a fish pedicure
325. Relax in a sensory deprivation tank
326. Recreate a childhood recipe
327. Blow glass
328. Learn to play chess
329. Get kissed on New Year’s Eve
330. Have a white Christmas
331. Join a book club
332. Skinny dip
333. Find a pearl in an Oyster
334. See an Opera
335. Ride in a tuk tuk
336. Go on a Caribbean cruise
337. Write a song
338. Attend a movie premiere
339. Attend a jazz festival
340. Get a caricature drawing by a street artist
341. Go to a book signing
342. Ride on a Ferris wheel
343. Ride in a gondola
344. See a TED Talk live
345. Find your signature scent
346. Get a henna tattoo
347. Make a will
348. Stay in a 5-star hotel
349. Cook a traditional dish from a different culture
350. Jump into a pool fully clothed
351. Win an award
352. Celebrate a holiday in a different culture
353. Explore a rainforest
354. Become someone’s mentor
355. Be present at a birth
356. Complete 100 hours of volunteer work
357. Change someone’s life for the better
358. Start a blog
359. Experience a new religion
360. Give a TED Talk
361. See a Tour de France
362. Read a banned book
363. Sing your heart out on a Tomorrowland festival
364. Take a cooking class from an Italian chef 
365. Sleep under the stars 
366. Catch a flamenco show in Barcelona, Spain
367. Learn to meditate in an ashram in India
368. Be someone’s maid of honour/best man
369. Go on a school reunion
370. Forgive someone
371. Horseback ride on a beach
372. Hug a sequoia tree
373. See a coral reef
374. Learn Spanish
375. Meet the Dalai Lama
376. Pay for someone’s shopping
377. Teach a class
378. Take a mud bath
379. Work until you no longer need to introduce yourself
380. Visit Tiffany in New York
381. Eat Ethiopian food with your hands
382. Savour coffee at Cafe de Flore, Paris
383. Visit Hallstatt, Austria
384. Sleep in a stable on a haystack
385. Make a snowman
386. Bath in the Spring Baths in Saturnia, Italy
387. Ride in a double-decker bus in London
388. Ice skate in Central Park
389. Watch a sunset from an aeroplane
390. Hug a penguin
391. Sit in a hot tub in winter
392. Visit the Haiku Stairs in Oahu, Hawaii
393. Milk a cow
394. Take your dream car for a test drive
395. Read philosophy
396. Write a letter to your future self
397. Step foot on the Normandy beach
398. Witness a solar eclipse
399. Visit Notting Hill, London
400. See Mont Saint Michelle, France
401. Sleep in a yurt
402. Sleep in an igloo
403. Fall in love
404. Go whale watching
405. Climb the steps of the Mayan ruins
406. Stomp grapes in Italy
407. Scuba dive in the Great Barrier Reef
408. Have a home library
409. Learn to read Braille
410. Travel with your best friend
411. Ride the subway in New York
412. Visit a black sand beach
413. Visit Santa’s Village in Finland
414. Go for an early morning stroll on a quiet street
415. Give people a reason to remember your name 
416. Visit every country on Earth.
417. See the Chichen-Itza in Yucatan Mexico
418. Experience zero gravity 
419. Have a cosy winter night in a chalet
420. Try pizza napolitanna in Napoli
421. Stay in an underwater hotel
422. Be in a parade 
423. Go dogsledding in Tromsø in Northern Norway
424. Step foot on the Arctic circle
425. Learn how to surf
426. Watch a meteor shower
427. Hike the Appalachian Trail
428. Drive Highway 1 in California
429. Take a trip around the World in 80 days
430. See the view from the Empire State Building, NYC
431. Set a Guinness World record
432. Take a trip with friends
433. Quit your job and do something you love for a year
434. Become an expert in your field
435. Conquer a lifelong fear
436. Visit Alaska
437. Learn another alphabet
438. Walk on the Equator line
439. See the Berlin Wall
440. See the Scottish Highlights
441. Tell someone your entire life story without omitting details
443. Do everything on the above list 

… this is an evergrowing list, so I’d very much appreciate suggestions